In life, we often encounter challenges that test our strength, courage, and faith. One of the most difficult trials comes when we face enemies—whether they are individuals who seek to harm us, situations that seem beyond our control, or even spiritual forces that oppose us. These enemies can come in various forms, causing distress, fear, and uncertainty. In these moments, we are reminded of the importance of turning to prayer and seeking divine intervention and protection.
Throughout history, prayer has been a powerful tool in overcoming adversity and fighting against those who seek to harm us. The Bible is rich with examples of individuals who faced enemies, both physical and spiritual, and found victory through prayer. From David’s psalms to the prayers of Jesus, we are reminded that God is our ultimate protector, and through faith and prayer, we can stand strong against any enemy.
This article, “Prayer Against Enemies,” offers a collection of 34 powerful prayers designed to help you seek protection, strength, and deliverance from various forms of opposition. Each prayer is tailored to address specific situations, whether you are facing enemies in high places, dealing with deceitful friends, or battling unseen spiritual forces. Through these prayers, you will find comfort and guidance as you trust in God’s power to shield you from harm.
Every prayer is accompanied by a Bible verse that highlights the promises of God’s protection, justice, and deliverance. These scriptures remind us that we are not alone in our struggles—God is always present, ready to fight on our behalf. Whether you are looking for peace, wisdom, or victory, these prayers will provide the spiritual strength you need to overcome the attacks of the enemy.
As you read through these prayers, take a moment to reflect on the challenges you face and allow these words to strengthen your faith. Remember that no matter how powerful or persistent the enemy may seem, our God is greater, and through prayer, we can find the victory that has already been secured for us. Let these prayers be a source of comfort and power as you seek God’s protection and deliverance in every area of your life.
37 Effective Prayers Against Enemies in 2025
1. A Prayer for Deliverance from Enemies
Dear God, I come before You seeking deliverance from my enemies. I ask that You protect me from those who seek to harm me and give me strength to overcome every obstacle they may place in my path. May Your angels surround me and shield me from their attacks. Lord, let Your power be made evident as You deliver me from all evil.
Psalm 34:17
“The righteous cry out, and the Lord hears them; he delivers them from all their troubles.” I trust in Your promise of deliverance, knowing that You are my refuge and strength in times of need.
Prayer
Father, I pray for Your protection over my life. Please guard my heart, my mind, and my soul from the plans of my enemies. I place my trust in Your ability to deliver me from all evil. Fill me with peace as I wait for Your intervention. Lord, give me the courage to walk through these trials with faith, knowing that You are always by my side. Amen.
2. A Prayer for Strength Against Enemies
Lord, I pray for the strength to withstand the attacks of my enemies. When they seek to weaken me, may Your power rise within me and make me strong. Grant me wisdom and resilience to face every challenge they present. With You by my side, I know I will not fall.
Isaiah 41:10
“So do not fear, for I am with you; do not be dismayed, for I am your God. I will strengthen you and help you; I will uphold you with my righteous right hand.”
Prayer
Dear God, I ask for Your strength to rise above the challenges brought by my enemies. Help me to stand firm and trust in Your might to carry me through. When I feel weak, may Your strength be made perfect in me. Remind me that You are always my rock and refuge, and in You, I can conquer anything. Amen.
3. A Prayer for Protection from Evil Forces
Heavenly Father, I seek Your protection from the evil forces that seek to harm me. I pray that You place a hedge of protection around me, my loved ones, and all that concerns me. Guard my steps and shield me from any evil that seeks to come near.
2 Thessalonians 3:3
“But the Lord is faithful, and he will strengthen you and protect you from the evil one.”
Prayer
Lord, I thank You for Your promise of protection. I ask that You keep me safe from all forms of evil, whether seen or unseen. Surround me with Your angels and cover me with Your blood. May no weapon formed against me prosper, and may I walk in Your divine protection every day. Amen.
4. A Prayer for Peace Amidst Enemies
Lord, in the face of my enemies, I ask for Your peace that surpasses all understanding. Calm my heart and mind, and help me remain still in Your presence, knowing that You are in control. Let Your peace reign over every storm.
Philippians 4:7
“And the peace of God, which transcends all understanding, will guard your hearts and your minds in Christ Jesus.”
Prayer
Father, grant me Your peace today. When I feel threatened by the presence of my enemies, let Your peace fill me. May I rest in the assurance that You are my protector and my guide.?Calm my fears and help me trust in Your perfect plan. I know that with You, I am safe. Amen.
5. A Prayer for Divine Justice
God of justice, I ask that You step into my situation and bring justice where there is wrong. Expose the evil of my enemies and let their schemes be revealed. I trust in Your timing and Your ability to make things right.
Psalm 103:6
“The Lord works righteousness and justice for all the oppressed.”
Prayer
Lord, You are the righteous judge, and I trust in Your ability to right the wrongs against me. I ask that You deal with my enemies according to Your justice. May Your righteousness prevail, and may I witness Your hand of justice in my life. I place my situation in Your hands, trusting You will handle it. Amen.
6. A Prayer for Wisdom in Dealing with Enemies
Lord, I seek Your wisdom in how to deal with my enemies. Please guide me in my actions, words, and thoughts, so that I may respond in ways that honor You. Help me to discern the best course of action in all situations.
James 1:5
“If any of you lacks wisdom, let him ask of God, who gives to all liberally and without reproach, and it will be given to him.”
Prayer
Father, grant me Your wisdom as I navigate challenges with my enemies. Help me to respond with grace, understanding, and strength. May I not act out of anger, but by Your will. Guide my steps and help me walk in a way that brings honor to Your name. Amen.
7. A Prayer for Overcoming Negative Words
Lord, I lift to You every word spoken against me by my enemies. I pray that You silence the mouths of those who seek to harm me with their words. Let their negative words fall to the ground without effect.
Isaiah 54:17
“No weapon forged against you will prevail, and you will refute every tongue that accuses you.”
Prayer
Lord, I declare that no weapon, including words, formed against me shall prosper. I pray that You render the words of my enemies powerless and ineffective. Surround me with Your protection and fill my heart with Your truth. May the words of others never define my worth. Amen.
8. A Prayer for Exposure of Hidden Enemies
Father, I pray that You expose every hidden enemy and their plans. Reveal the truth about those who secretly seek my downfall, and bring their plots into the light.
Luke 12:2
“There is nothing concealed that will not be disclosed, or hidden that will not be made known.”
Prayer
Lord, I trust that You will reveal the true intentions of those around me. Expose every hidden enemy and protect me from their secret plans. May their strategies fail as Your light shines on their deceit. I place my trust in Your justice and truth. Amen.
9. A Prayer for Protection from Physical Attacks
Lord, I pray for protection from physical harm. Cover me with Your shield of protection and guard me from any danger or harm that may come my way.
Psalm 91:4
“He will cover you with his feathers, and under his wings you will find refuge; his faithfulness will be your shield and rampart.”
Prayer
Father, I ask that You shield me from any physical harm or danger. I trust in Your protection and know that You are with me, watching over me. Keep me safe from accidents, attacks, or any other form of harm. I place my body and my life in Your hands. Amen.
10. A Prayer for Deliverance from Slander
Lord, I ask for Your help in overcoming the slander spoken about me. Please defend my name and reputation from false accusations and malicious words.
Psalm 140:11
“Let not the slanderer be established in the earth; let evil hunt the violent man to overthrow him.”
Prayer
Father, I pray for the strength to endure slander and false accusations. Please protect my name and reputation. Defend me from those who seek to harm me with their words. May their lies be exposed, and may Your truth prevail. Amen.
11. A Prayer for Protection from Spiritual Attacks
Heavenly Father, I come before You seeking protection from all spiritual attacks. Guard my spirit and soul from the forces of darkness that try to weaken my faith. I pray for Your strength to resist temptation and to stand firm in Your Word.
Ephesians 6:11
“Put on the full armor of God, so that you can take your stand against the devil’s schemes.”
Prayer
Lord, I ask for Your armor to cover me today. Protect my heart, mind, and soul from the attacks of the enemy. Help me stand firm in Your truth, and equip me with Your Word to resist any temptation. May Your presence be a constant shield that keeps me safe from spiritual harm. Amen.
12. A Prayer for Deliverance from Betrayal
Lord, I seek deliverance from the pain of betrayal. Heal my heart from the hurt caused by those who have turned against me. May Your grace bring me peace, and help me forgive those who have wronged me.
Psalm 55:12-14
“If an enemy were insulting me, I could endure it; if a foe were raising himself against me, I could hide from him. But it is you, a man like myself, my companion, my close friend, with whom I once enjoyed sweet fellowship at the house of God, as we walked about among the worshipers.”
Prayer
Father, I ask that You heal my heart from the sting of betrayal. Help me to forgive those who have hurt me, and may Your love fill the void left by their actions. I place my trust in You to bring justice and healing. Lord, strengthen me as I move forward, and may I never allow betrayal to diminish my faith in You. Amen.
13. A Prayer for Victory Over Enemies
Almighty God, I pray for victory over all my enemies. Please give me the strength and wisdom to overcome every challenge and obstacle they place in my path. May Your power be displayed in my life, leading me to triumph.
Romans 8:37
“No, in all these things we are more than conquerors through him who loved us.”
Prayer
Lord, I thank You for the victory that is mine in Christ Jesus. I stand firm in Your promises, knowing that through Your strength, I will overcome every enemy. May Your power be evident in my life as I face every challenge. I declare victory in Your name. Amen.
14. A Prayer for Divine Intervention in Times of Persecution
God, I seek Your intervention during times of persecution. Please intervene on my behalf and protect me from the harm and suffering caused by those who seek to persecute me.
Matthew 5:10
“Blessed are those who are persecuted because of righteousness, for theirs is the kingdom of heaven.”
Prayer
Father, I thank You for Your promise of blessing amid persecution. Please strengthen me as I endure the trials and suffering brought by my enemies. May Your hand of protection be upon me, and may Your grace give me the courage to stand firm in righteousness. Amen.
15. A Prayer for Peace Amid Conflict
Lord, I seek peace amid conflict. When my enemies surround me with strife and discord, I pray that Your peace reigns in my heart and mind. Help me to be a peacemaker, even in difficult circumstances.
Matthew 5:9
“Blessed are the peacemakers, for they will be called children of God.”
Prayer
Lord, grant me peace even when I face conflict. Help me to respond to my enemies with grace and understanding, and may Your peace guide me in all things. Let my actions reflect Your love, and may I be a source of peace to those around me. Amen.
16. A Prayer for Protection from Harmful Influences
Proverbs 4:23
“Above all else, guard your heart, for everything you do flows from it.”
Prayer
Lord, please protect my heart and mind from any harmful influences. Help me to stay rooted in Your Word and remain strong against any distractions or attacks. Keep me focused on You, and help me to avoid the temptations my enemies may use against me. Amen.
17. A Prayer for Protection from False Accusations
Lord, I ask for Your protection from false accusations made by my enemies. Please defend my character and reputation, and expose the lies being spoken about me.
Psalm 7:3-4
“Lord my God, if I have done this and there is guilt on my hands— if I have repaid my ally with evil or without cause have robbed my foe— then let my enemy pursue and overtake me.”
Prayer
Father, I trust that You will protect me from false accusations. Please defend my name and reputation from those who seek to tarnish them with lies. May Your truth shine through, and may the enemy’s lies be exposed for what they are. Amen.
18. A Prayer for Wisdom in Handling Enemies
God, grant me the wisdom to handle my enemies wisely. Help me to approach every situation with discernment, seeking Your guidance in how to respond.
Proverbs 2:6
“For the Lord gives wisdom; from his mouth come knowledge and understanding.”
Prayer
Lord, I ask for Your wisdom in all my dealings with my enemies. Help me to respond in ways that honor You and reflect Your love. May Your understanding guide my decisions and actions, and may I walk in peace, even when confronted by those who oppose me. Amen.
19. A Prayer for Protection from Jealous Enemies
Lord, I pray for protection from the jealousy of my enemies. Keep me safe from their envy and prevent their schemes from succeeding.
Proverbs 3:31
“Do not envy the violent or choose any of their ways.”
Prayer
Father, protect me from the jealousy and envy of those who seek to harm me. May their plans not succeed, and may I not be swayed by their negative energy. Help me to focus on Your purpose for my life and trust that You are in control. Amen.
20. A Prayer for Healing from Enemy Attacks
Lord, I pray for healing from any emotional or physical wounds caused by my enemies. Please restore me and bring me peace as I recover from their attacks.
Jeremiah 30:17
“But I will restore you to health and heal your wounds,’ declares the Lord, ‘because you are called an outcast, Zion for whom no one cares.'”
Prayer
Father, I ask for Your healing touch upon me. Heal the wounds inflicted by my enemies, whether emotional, physical, or spiritual. Restore me to full health and renew my strength. May I emerge from this trial stronger and more steadfast in my faith? Amen.
21. A Prayer for Protection from Gossip
Lord, protect me from the destructive power of gossip. Keep me safe from those who spread rumors or falsehoods about me, and help me to remain strong in Your truth.
Proverbs 20:19
“A gossip betrays a confidence; so avoid anyone who talks too much.”
Prayer
Father, please guard me from the hurt caused by gossip. Keep me from engaging in any negative talk, and protect my name from those who wish to destroy it. May Your truth prevail, and may I always speak with love and kindness. Amen.
22. A Prayer for Protection from Enemies in High Places
Lord, I seek Your protection from those in positions of power who may use their authority to harm or oppress me. I ask that You shield me from their schemes and guide me toward safety.
Psalm 37:32
“The wicked lie in wait for the righteous, intent on killing them; the Lord will not leave them in their power or let them be condemned when brought to trial.”
Prayer
Father, I place my trust in You, knowing that You will protect me from those in high places who seek to harm me. I ask that You expose their plans and frustrate their efforts. May Your justice prevail, and may Your protection be evident in every area of my life. Amen.
23. A Prayer for Deliverance from Enemies Who Seek My Downfall
Heavenly Father, I ask for Your deliverance from the enemies who seek my downfall. Please break their power over my life and protect me from any attack designed to destroy me.
Psalm 54:5
“Let evil recoil on those who slander me; in Your faithfulness destroy them.”
Prayer
Lord, I pray for Your divine intervention in the face of enemies who seek to destroy me. Please frustrate their efforts and bring about my deliverance. Protect me from all harm, and may I find refuge under Your wings. Thank You for Your unfailing protection. Amen.
24. A Prayer for Protection from False Friends
Lord, I pray for protection from those who claim to be my friends but harbor malicious intentions. Expose their deceitful hearts and help me surround myself with genuine people who seek my well-being.
Proverbs 27:6
“Wounds from a friend can be trusted, but an enemy multiplies kisses.”
Prayer
Father, please help me discern true friends from false ones. Protect me from those who pretend to be allies but seek to harm me. Surround me with trustworthy people who genuinely care for me. Grant me wisdom to recognize and avoid deceptive relationships. Amen.
25. A Prayer for Justice Against Enemies
Lord, I ask for Your justice to prevail over those who have wronged me. Please fight my battles and ensure that justice is served according to Your will.
Psalm 43:1
“Vindicate me, my God, and plead my cause against an unfaithful nation; rescue me from those who are deceitful and wicked.”
Prayer
Father, I place my trust in You to bring about justice in my life. Defend my cause and expose the evil schemes of my enemies. Let Your righteousness shine through and bring peace to my heart. Thank You for being my advocate and my defender. Amen.
26. A Prayer for Protection from Enemies Who Use Witchcraft
Lord, I pray for protection from any enemies who attempt to use witchcraft or other evil practices against me. May Your power nullify their efforts and render them powerless.
Exodus 22:18
“Do not allow a sorceress to live.”
Prayer
Father, I ask that You protect me from the evil practices of witchcraft. Please nullify every curse, hex, or spell cast against me. Surround me with Your divine protection and keep me safe from all forms of darkness. In Jesus’ name, I declare that no weapon formed against me shall prosper. Amen.
27. A Prayer for Wisdom in Dealing with Enemies
Heavenly Father, grant me wisdom in how to handle situations with my enemies. Teach me to respond with grace, discernment, and strength, knowing that You are always with me.
James 1:5
“If any of you lacks wisdom, let him ask of God, who gives to all liberally and without reproach, and it will be given to him.”
Prayer
Lord, I ask for Your wisdom in dealing with the challenges posed by my enemies. Help me to see through deception and make decisions that align with Your will. May Your Holy Spirit guide me and grant me the strength to remain calm and collected in every situation. Amen.
28. A Prayer for Victory Over Enemies Who Plan in Secret
Lord, I ask for victory over the enemies who plan in secret to harm me. Expose their hidden plots and frustrate their plans before they can come to fruition.
Psalm 64:2-4
“Hide me from the conspiracy of the wicked, from the noisy crowd of evildoers. They sharpen their tongues like swords and aim cruel words like deadly arrows.”
Prayer
Father, I pray that You expose the hidden plans of my enemies. Bring their schemes into the light and prevent them from causing harm. May Your divine protection be upon me, and may I find refuge under Your wings. Amen.
29. A Prayer for Protection from Enemies Who Speak Lies
Heavenly Father, protect me from enemies who speak lies about me. Please defend my reputation and bring the truth to light.
Psalm 120:2-3
“Save me, Lord, from lying lips and from deceitful tongues. What will he do to you, and what more besides, you deceitful tongue?”
Prayer
Lord, I ask for Your protection from lies and deceit. Guard my heart and mind, and expose any falsehoods spoken against me. May Your truth prevail, and may I remain steadfast in Your righteousness. Thank You for defending my honor and reputation. Amen.
30. A Prayer for Deliverance from Enemies Who Seek to Harm My Family
Father, I pray for Your protection over my family. Deliver us from all harm and protect us from any enemies who seek to bring destruction into our lives.
Psalm 91:14-15
“Because he loves me,” says the Lord, “I will rescue him; I will protect him, for he acknowledges my name. He will call on me, and I will answer him; I will be with him in trouble, I will deliver him and honor him.”
Prayer
Lord, I pray for Your protection over my family. Deliver us from any harm, and keep us safe from the plans of our enemies. May Your angels guard us and Your peace fill our hearts. Thank You for being our refuge and fortress in times of trouble. Amen.
31. A Prayer for Strength to Endure the Attacks of the Enemy
Lord, give me the strength to endure the attacks of the enemy. When I am weak, help me find my strength in You, and let me remain steadfast in my faith.
Isaiah 40:29
“He gives strength to the weary and increases the power of the weak.”
Prayer
Father, when I face the attacks of the enemy, give me strength. Help me to stand firm in my faith, knowing that You are with me. Renew my spirit and help me persevere through every trial. I trust in Your strength to carry me through. Amen.
32. A Prayer for Protection from Enemies Who Use Deception
Lord, protect me from enemies who use deception and manipulation to harm me. Expose their lies and help me to remain true to Your Word.
Proverbs 12:5
“The plans of the righteous are just, but the advice of the wicked is deceitful.”
Prayer
Father, I pray for protection from deception. Expose the lies of my enemies and give me discernment to recognize the truth. Help me to stay grounded in Your Word and to trust in Your wisdom. Amen.
33. A Prayer for Freedom from Enemies Who Hold Me Captive
Heavenly Father, I ask for freedom from any enemies who seek to hold me captive, whether physically, emotionally, or spiritually.
Isaiah 61:1
“The Spirit of the Sovereign Lord is on me, because the Lord has anointed me to proclaim good news to the poor. He has sent me to bind up the brokenhearted, to proclaim freedom for the captives and release from darkness for the prisoners.”
Prayer
Lord, I pray for freedom from any form of captivity. Release me from the chains that bind me, and protect me from those who seek to keep me in bondage. May Your Spirit bring healing, restoration, and liberation. Amen.
34. A Prayer for Peace in My Heart Despite the Attacks of My Enemies
Lord, I ask for peace in my heart despite the attacks of my enemies. Help me to trust in Your protection and to remain calm and composed in the face of adversity.
Philippians 4:7
“And the peace of God, which transcends all understanding, will guard your hearts and your minds in Christ Jesus.”
Prayer
Father, grant me peace in my heart that surpasses all understanding. Help me to remain calm and trust in Your protection, knowing that You are my refuge and strength. May Your peace guard my heart and mind as I face the challenges ahead. Amen.
Conclusion
In conclusion, the power of prayer cannot be underestimated, especially when facing adversaries, whether they are physical, emotional, or spiritual in nature. As believers, we are assured by God’s Word that He is our refuge and fortress, always ready to protect and deliver us from harm. The prayers shared in this article are designed to empower you to stand firm against the attacks of the enemy, reinforcing the belief that God’s protection is ever-present and His justice will prevail.
Each prayer, supported by a Bible verse, serves as a reminder that God is a stronghold for those who trust in Him. Whether you are up against human foes, negative circumstances, or invisible spiritual forces, these prayers provide the tools necessary to invoke God’s divine intervention. By consistently turning to Him in prayer, you are aligning yourself with His strength, wisdom, and protection. He has promised to fight for us, and as we engage in prayer, we can rest in the assurance that victory is already within our reach.
No matter the nature of the enemies you face, always remember that you are never alone. With God by your side, you have access to His unlimited power to overcome any opposition. He hears your prayers and responds according to His will, bringing peace, justice, and deliverance in His perfect timing.
As you continue in your journey of faith, let these prayers be a source of strength and inspiration. Let them remind you that no enemy is too great for the Almighty God. Stand firm, pray with boldness, and trust that victory is assured. God is your protector, and with Him, you are more than a conqueror. Keep pressing forward, knowing that His divine hand is always with you.
